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A Review of the Aetiology and Management of Sinonasal Inverted Papilloma

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Inverted papilloma (IP) is histologically a benign disease, but it has long been recognised as warranting aggressive surgical management. It has a propensity to be locally destructive, has high rates of recurrence, and a strong association with malignant transformation. Aetiology of IP is still uncertain, but Human Papilloma Virus (HPV) is implicated and, in a similar manner to cervical HPV infection, is proposed to have a role in malignant change occurring within IP. A review of recent literature on the aetiology of IP and possible predictors of recurrence and malignant potential is presented. Krouse’s staging of IP is discussed, with a recently published modification, adjusted for prognostic factors. Results of endoscopic and open surgery, with long-term follow-up are reviewed.

Additional Info

  • Authors: Robinson Simon, Murphy Justin & Mills Nikki
  • Keywords: Sinonasal inverted papilloma, schneiderian papilloma, inverting papilloma, sinonasal neoplasm, human papilloma virus, HPV, squamous cell carcinoma.
Read 6721 times Last modified on Tuesday, 10 December 2013 13:31